ASBL


Automated Synthetic Biology Labs

ASBL makes robotic labs for hands-free experiments. Ditch the gloves, be a keyboard bioengineer.

Contact: manonthemoon13131@gmail.com

Products in ASBL:

1. ASBL Lab 0 ($500,000): automated cell feeder
This machine feeds bacterial and mammalian cells to keep cells alive. ASBL Lab 0 integrates a liquid handler, plate reader, incubator, refrigerator, cell counter, and robotic arm. Use with Python.

2. ASBL 1 ($1 million): automated bacterial genetic engineer
This machine genetically engineers E. coli K12 cells. ASBL Lab 0 + template plasmid synthesis + purification + transformation integrations. This machine outputs a genetically engineered bacterial colony given an input plasmid. Use with Python.

3. ASBL II ($10 million): automated mammalian genetic engineer
Lipid nanoparticle mRNA transfection expressed in 96 wells per cycle. Use with Python.

Software:

4. HumanGEMlib Python library for human genome-scale modeling. HumanGEM (1) comprehensive human reaction network, and COBRApy (flux balance analysis) power HumanGEMlib to simulate effects of genetic knockouts on human metabolism. Type 2 diabetes signature metabolisms reported here.

Drug pipeline:

5. Mohsina (preclinical): insulin replacement for insulin-resistant type 2 diabetes. Messenger RNA (mRNA) and antisense oligonucleotide (ASO) combinations combat metabolic dysregulation.

6. MID (preclinical): insulin replacement for insulin-deficient type 2 diabetes

Projects in ASBL:

7. Matrixims: brain organoids (3) playing The Sims

8. Deconstructed human: organoid (4,5) bioreactors for testing

9. Protein laser conjugated with quantum dot

10. Cellular agriculture of wasabi and truffles

11. ASBL 4: automated meat printer

12. Microtubules in carbon nanotube applications

13. Small molecule targeted delivery

ASBL INC. is incorporated in Delaware, United States.

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